ea0032p338 | Developmental Endocrinology | ECE2013
Soeborg Tue
, Frederiksen Hanne
, Johannsen Trine Holm
, Juul Anders
, Andersson Anna-Maria
Diagnosis and management of infants and children with sex steroid disorders requires fast and simultaneous assessment of several sex steroid metabolites in serum at low concentrations and on small sample volumes. Therefore, we developed a sensitive and selective TurboFlow-LC-MS/MS method for quantification of DHEA, DHEAS, 17α-hydroxyprogesterone, Δ4-androstenedione and testosterone in serum from pre-pubertal children.Total run time was 10.75 mi...